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Genmab has stopped enrolling patients in an early-stage clinical trial for an experimental cancer drug it gained through the acquisition of ProfoundBio in April 2024 for €1.52 billion. This pause underscores a broader reshaping of its oncology strategy.
UK biotech is heading into 2026 with a growing sense of momentum, even as the sector continues to navigate one of the most selective investment climates in years.
The U.K. biotech Ellipses Pharma, which develops cancer therapeutics, announced a collaboration and licensing agreement with China-based Innolake Biopharm Co. Ltd to develop a clinical-stage, first-in-class antibody–drug conjugate (ADC), EP0028, for solid tumors.
Unexpected changes at the top of Rentschler Biopharma: CEO Benedikt von Braunmühl and the Supervisory Board agreed on a swift separation in January, and COO Christiane Bardroff is also set to leave the biopharma manufacturer based in Laupheim, Baden-Württemberg, in the near future. The message from within the company: stay calm, it won´t knock us off course.
Four months after the FDA advised it against filing for approval of its lead melanoma vaccine, IO Biotech is preparing for further restructuring. The Copenhagen-based biotech said yesterday that it is exploring strategic alternatives, including a merger, asset sale, business combination, or potential liquidation, and warned that it may need to implement additional workforce reductions and cost-cutting measures as the process unfolds.
Infinitopes, a U.K. cancer vaccine biotech spun out of Cancer Research U.K. and the University of Oxford, has expanded its seed round to $35.1 million after a second close that added about $15.4 million to existing commitments. The financing was co-led by Octopus Ventures and new investor Amplify Bio. The company says the funds will support its upcoming first-in-human phase 1/2a VISTA trial of its lead therapeutic vaccine, ITOP1, aimed at reducing post-surgical recurrence in oesophageal cancer.
The Westin St. Francis lobby buzzed with its familiar January energy, a peculiar blend of jet lag, ambition, and the faint desperation of biotech CEOs clutching coffee cups like lifelines. This year’s JP Morgan Healthcare Conference arrived with a question hanging in the San Francisco fog: after years of what one executive called “nuclear winter,” were the capital markets finally thawing?
With the departure of the current CEO of diagnostics company Qiagen NV (Venlo, Netherlands/Hilden, Germany) and before a new chief executive has been identified and presented, there appears to be activity at senior management level, according to Bloomberg, around whether a sale of the company or the admission of a major strategic partner could be an alternative. These rumours have sent the share price sharply higher.
The French preclinical-stage biotech ErVimmune closed a €17 million series A round to bring its lead candidate cancer vaccine into the clinic.
GSK has agreed to acquire California-based RAPT Therapeutics in a deal valued at $2.2 billion (€ 1.88 billion), expanding its respiratory, immunology and inflammation portfolio with a late-stage food allergy candidate. The transaction gives GSK global rights to ozureprubart, a long-acting anti-IgE monoclonal antibody now in phase IIb clinical development.