AZ checkpoint blocker combo fails in head and neck cancer

British drugmaker AstraZeneca (AZ) has missed another opportunity to secure a share in the lucrative immunoncology market: a Phase III trial combining durvalumab with tremelimumab missed the survival endpoint.

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BioFIT: innovation and investors

For two days, Lille was the place to be for partnering in early stage innovation. On December 5th, Europe’s leading tech transfer event BioFIT wrapped up, recording a record number of participants.

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Uncommon mutations affect breast cancer prognosis

Uncommon mutations in three genes in estrogen receptor positive breast cancer have a negative impact on disease prognosis reports a team of British and Australian researchers in Nature Communications. 


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Argenx in US$1.6bn deal with J&J affiliate Janssen

Janssen affiliate Cilag GmbH International has licenced argenx’ anti-CD70 antibody cusatuzumab (ARGX-110) for US$300m upfront.

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Driver of GVHD after blood stem cell transplantation identified

Swiss, French and German researchers have unraveled a molecular pathway that might be useful to prevent Graft-versus-Host Disease (GVHD) in leukemic recipients of blood stem cell transplants.

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Investors pool €27m for new Proteomics tech

UK-based biotech startup Fluidic Analytics has raised €27m for its proteomics platform. The financing round was led by Draper Esprit, with participation from Delin Ventures, BGF, IQ Capital, and Amadeus Capital Partners. 

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Carbios set to build closed-loop PET plant

French Carbios SA has signed a letter of intent with PVC giant Kem One to implement a demonstration plant to provide proof of concept of Carbios‘ groundbreaking enzymatic PET depolymerisation technology.

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Adrenomed bags €24m in growth financing

German Adrenomed AG has bagged €24m in equity financing from HBM Healthcare Investments and Wellington Partners.

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Roche targets asthma with inhalable JAK1 blocker

Researchers at Genentech have locally blocked lung inflammation in a mouse model for asthma by administration of an inhalable JAK1 inhibitor.

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