Foundation launches £30m award
The British Heart Foundation (BHF) will tender £30m (33.2m) to tackle the suffering and devastation caused by heart and circulatory diseases.
FDA greenlights Shires HAE mAB Takhzyro
Orphan drug leader Shire plc (Dublin), has received the FDAs approval for its antibody lanadelumab-flyo, which prevents hereditary angioedema (HAE) attacks.
Matrikines give hint to new asthma meds
Blocking the extracellular matrix (ECM) enzyme leukotriene A4 hydrolase (LTA4H) dampens inflammation but promotes changes in the airways of mice with allergic asthma due to accumulation of the ECM degradation product PGP.
Novo Nordisk joins Evotec as drug discovery partner
Novo Nordisk and Evotec have joined forces to find new drugs in the lucrative diabetes and obesity markets.
Genkyotex cashes in 7.5m
French Genkyotex SA has secured an 7.5m gross financing to expand the scope of its Phase II product GKT831 in Primary Biliary Cholangitis (PBC).
Roche’s Alecensa approved in China
Roche AGs ALK blocker Alecensa (alectinib) has been granted market approval by China National Drug Administration as first line NSCLC monotherapy in patients with ALK-positive non small cell lung cancer (NSCLC)
Pfizer partners with Biontech in US$425m deal
BioNTech AG has partnered with Pfizer to develop a mRNA-based flu vaccine.
New lupus target unraveled
EGFR agonists support the protective effect of Langerhans against UV-induced damage of skin cells, a hallmark of lupus erythematosus and other autoimmune and dermatologic conditions, a team of US and German researchers report.
Small molecule restores liver regeneration
A team of Scots, Belgian and Spanish researchers claim they have found a target to prevent failure of liver regeneration following intoxination or acute injury.
Orchard Therapeutics raise US-$150m
London-headquartered gene therapy Orchard Therapeutics has closed a US-$150m series C financing round to push MAAs and BLAs of three late-stage gene therapies by 2021.