Biomarker identifies residual congestion in heart failure patients

Data from 1,200 heart failure patients demonstrate that high discharge levels of the biomarker bio-ADM® (bioactive Adrenomedullin) indicate residual congestion in heart failure patients.

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Belgian start-up takes fight on neuropathies

The new company, named Augustine Therapeutics, is a Vlaams Instituut voor Biotechnologie (VIB) and Katholieke Universiteit (KU) Leuven spin-off. Funded with €4.2m from mainly local investors, Augustine’s first priority is finding new therapeutics for patients suffering from Charcot-Marie-Tooth disease, a hereditary motor and sensory neuropathy of the peripheral nervous system.

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Second clinical failure of Transgene in 2019

French Transgene SA said it has terminated its lead programme TG4010 in combination with chemotherapy and checkpoint inhibition. 

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Microbiota contribute to skin damage in cancer therapy

New research demonstrates that disruption of EGF receptor signalling allows commensal bacteria to invade hairs and cause skin lesions.

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BIOncoTech Therapeutics and MSD combine cancer drugs

Madrid-based RNA specialist Bioncotech Therapeutics has entered into a Phase II clinical trial collaboration with a MSD subsidiary.

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Urokinase clears blot clots in stroke patients

Swiss surgeons have significantly improved mechanical removal of blood clots in stroke patients by intra-arterial administration of the thromolytic urokinase.

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Sanofi buys Synthorx Inc for US$2.35bn

Sanofi will acquire Synthorx Inc to expand its  immuno-oncology pipeline with THOR-707, an optimised IL-2 candidate.

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Meatable NV raises US$10m in seed funding

Meatable NV, a specialist for cultivated meat, has raised an additional US$10m in seed funding, bringing the company’s total funding to US$13m.

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Big Pharma is cost driver of GAVI

Médecins Sans Frontières (MSF) called on the GAVI Vaccine Alliance not to pay huge subsidies to Big Pharma companies for pneumococcal vaccine

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ImCheck Therapeutics SAS raises €48m

T cell agonist specialist ImCheck Therapeutics will use €48m (US$53m) from a Series B financing to push clincial pipeline of antibodies activating gamma-delta T-cells.

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