Sequencing-ready DNA for fast Molecular Breeding results

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BioEcho develops single-spin and 96-well kits for the isolation of DNA from different starting materials. Their proprietary EchoLUTION single-step technology avoids the use of inhibitory process reagents while using dedicated efficient lysis reagents for e.g. different plant tissues. In contrast to common bind-wash-elute procedures, the process does not require washing steps. The inhibitor-free DNA enables lowered time-to-result in enzyme-dependent genomic analyses such as PCR or NGS.

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Immatics and Celgene enter $1.5bn deal

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Celgene will pay $75m upfront to get an option on three cancer programmes developed by Immatics Biotechnologies.

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Microbial feed company Unibio raises US$15m

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Danish microbiology specialist Unibio International plc had completed a US$15m financing round led by West Hill Capital.

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GSK reaches endpoint in pivotal blood cancer study

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GlaxoSmithKline plc announced belantamab mafodotin (GSK2857916) met the primary endpoint of overall response rate (ORR) in a pivotal Phase II trial in treatment-refractive multiple myeloma.

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Swiss researchers report on metastasis switch

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Researchers from Paul Scherrer Institute in Villingen, Switzerland, and Hoffmann La-Roche AG report in Cell they have solved the structure of a target relevant in metastasis.

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Preclinical antibody stops rheumatoid arthritis

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An antibody therapy that targets red blood cells (RBCs) unexpectedly showed anti-inflammatory effects and rapidly reversed rheumatoid arthritis and prevented lung injury in mouse models. 

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Nabriva receives FDA approval for novel antibiotics

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Nabriva Therapeutics plc has got the go from the FDA to market its pleuromutilin antibiotic Xenleta (lefamulin), a protein synthesis blocker with new mode-of-action to treat community-acquired bacterial pneumonia.

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Araris Biotech AG kicks-off with CHF2.5m seed financing

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Zurich-based ADC maker Araris Biotech AG announced the closing of an oversubscribed seed financing round of CHF2.5m with Redalpine, Schroder Adveq and VI Partners contibuting.

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PharmaMar moves ahead with NDA for Zepsyre

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The FDA has given the go-ahead to PharmaMar’s proposal to file for accelerated approval its New Drug Application (NDA) for lurbinectedin monotherapy for the treatment of second-line small-cell lung cancer.

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Swedish researchers find new pain organ

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Researchers at Karolinska Institutet have discovered a new sensory receptor organ that is able to detect painful mechanical damage, such as pricks and impacts.

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