Orchard plans to raise US$172m in ADS

British gene therapy developer Orchard Therapeutics will go IPO on Nasdaq, according to SEC filings. The company plans to raise $172.5m as ADS in an IPO underwritten by J.P. Morgan, Goldman Sachs, Cowen and Wedbush PacGrow to balance its costs, which rose from US$13m to US$138m this year. Financial markets are expected to react positively.

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Sphingotec raises €20m in growth equity financing

Diagnostics company sphingotec GmbH successfully closed a €20m growth equity financing round led by international specialist investors HBM Healthcare Investments, HBM BioCapital II LP (HBM) and Wellington Partners.

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Sanofi and Evotec launch drug discovery PPP

Evotec and Sanofi have launched a Public Private Partnership (PPP) aimed at partnering with academic groups in early stage drug discovery across multiple therapeutic areas. 

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Roche providing improved anti-Her2 bispecific antibody

Researchers at at VHIO in Barcelona, Spain, and Roche in Schlieren have presented a bi-specific antibody that prevents the side effects of HER2-targeting compounds.

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Forbion closes Life Sciences VC Fund at €360m

Life Sciences venture capitalist Forbion has closed its  new flagship fund, Forbion IV, at €360m, €90m above its original target of €250m.

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BIOSPAIN expanding

Matured, diversified and willing to expand – this is how the Spanish biotech sector presented itself during BIOSPAIN 2018 in Seville. Andalusia has launched the first bioeconomy policy strategy in Spain. 

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Minoryx bags €21.3m Series B financing

Barcelona-based Minoryx Therapeutics announced during BIOSPAIN 2018 it has raised another €21.3m in a Series B financing bringing its assets to a total of €50M. 

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PD-1+ T cells trigger pulmonary fibrosis

A team of researchers from the US and the UK have found that CD4-positive T cells harboring the PD-1 immune checkpoint protein can promote excessive connective tissue formation in lung cells. 

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CRISPR-gene drive safely kills mosquitos

A new gene drive can cause the complete collapse of caged malaria-carrying mosquito populations, researchers from Imperial College report in Nature Biotechnology. 

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CHMP with new Chair – 13 meds recommended

The CHMP elected Harald Enzmann as its new Chair on Friday, and recommended thirteen medicines for approval, three thereof orphan medicines.

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